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- Season 1 1993-08-30
- Season 2 1994-08-29
- Season 3 1995-09-04
- Season 4 1996-09-02
- Season 5 1997-09-01
- Season 6 1998-08-31
- Season 7 1999-09-07
- Season 8 2000-08-21
- Season 9 2001-08-20
- Season 10 2002-09-03
- Season 11 2003-09-01
- Season 12 2004-08-23
- Season 13 2005-08-29
- Season 14 2006-08-28
- Season 15 2007-09-04
- Season 16 2008-09-02
- Season 17 2009-08-31
- Season 18 2011-01-03
- Season 19 2012-01-03
- Season 20 2013-01-02
- Season 21 2014-01-06
- Season 22 2014-09-02
Season 22 Episode
- Season 15 Former President Bill Clinton, Patti Scialfa
- Season 15 Danny DeVito, Larry David, Avril Lavigne
- Season 15 Jessica Alba, George Saunders, The Manchester Orchestra
- Season 15 Rachael Ray, Frank Rich, Arctic Monkeys
- Season 15 Jodie Foster, Glen Hansard & Markéta Irglová
- Season 15 Dr. Phil McGraw, Andy Kindler, Suzanne Vega
- Season 15 Viggo Mortensen, Kat Von D, Daughtry, a Top Ten List presented by 10 NASCAR stars
- Season 15 Martha Stewart, Fred Willard, a Top Ten List presented by Billy Bob Thornton
- Season 15 Regis Philbin, Chamillionaire
- Season 15 Jamie Foxx, Jimmy Smits, Will.I.Am
- Season 15 Kate Walsh, Kevin Smith, Rascal Flatts
- Season 15 Jennifer Garner, Ken Burns, Chaka Khan
- Season 15 Stupid Human Tricks, Whoopi Goldberg, Melissa Etheridge
- Season 15 Paris Hilton, Emile Hirsch
- Season 15 Sean Penn, Barry Sonnenfeld, Ben Harper
- Season 15 Jude Law, Sarah Silverman, John Fogerty
- Season 15 Alec Baldwin, Faith Hill
- Season 15 Nicolette Sheridan, Tony Snow, Rihanna
- Season 15 Bob Newhart, Angela Kinsey, Iron and Wine
- Season 15 George Clooney, Kid Rock
- Season 15 Jennifer Lopez, Alan Greenspan
- Season 15 Stephen Colbert, Eva Mendes, Queens of the Stone Age
- Season 15 Anne Heche, Sue Johanson, Mariza
- Season 15 Halle Berry, Bill Hader, Spring Snake Symphony
- Season 15 Jake Gyllenhaal, Connie Britton, 50 Cent
- Season 15 Richard Simmons, Casey Affleck, Sondre Lerche
- Season 15 Rebecca Romijn, Jimmie Walker, LeAnn Rimes
- Season 15 Steve Carell, Chris Russo, Chris Elliott, Band of Horses
- Season 15 Amanda Peet, Patrick Warburton, Jeff Caldwell
- Season 15 Jerry Seinfeld, Joe Torre
- Season 15 Jennifer Connelly, Slash, Nicole Atkins
- Season 15 David Spade, Penn & Teller, Jonathan Papelbon
- Season 15 Dr. Phil McGraw, Ryan Adams
- Season 15 Bill Murray, Jay-Z
- Season 15 Robin Williams, Lupe Fiasco
- Season 15 Bill Maher, Ellen Page, the cast of Broadway's "Young Frankenstein"
- Season 15 Donald Trump, Shooter Jennings
- Season 15 Tom Hanks, Gov. Mike Huckabee
- Season 15 Lucy Liu, Alex Roy, MGMT
- Season 15 Morgan Freeman, Tom Brokaw, Chuck Prophet
- Season 15 Howard Stern, Ayo
- Season 15 Tracy Morgan, Kat Von D, Dropkick Murphys
- Season 15 Katie Holmes, Frank Caliendo, Maroon 5
- Season 15 Denzel Washington, Don Rickles
- Season 15 Michael Douglas, Katherine Heigl, Wyclef Jean
- Season 15 Sylvester Stallone, the Teutul family, the Mars Volta
- Season 15 Diane Keaton, Jim Gaffigan
- Season 15 Sarah Michelle Gellar, Dan Patrick, Ringo Starr
- Season 15 Sen. John Edwards, Diablo Cody, Josh Ritter, David "Fathead" Newman
- Season 15 Charles Grodin, New York Giant Lawrence Tynes, The Redwalls
- Season 15 Julia Louis-Dreyfus, T.J. Miller, Super Furry Animals
- Season 15 Nathan Lane, Jake Johannsen
- Season 15 Jessica Alba, Julie Chen, The Whigs
- Season 15 Bill Cosby, Lake Bell, The Matt Savage Trio
- Season 15 Dr. Phil McGraw, Lena Headey, Gary Allan
- Season 15 Stupid Human Tricks, Eva Longoria Parker, Colbie Caillat
- Season 15 Paris Hilton, Artie Lange, Vampire Weekend
- Season 15 Sen. Hillary Clinton, Sheryl Crow
- Season 15 Matthew McConaughey, Gary Mule Deer, Sheryl Crow
- Season 15 Eli Manning, Vince Vaughn, A Fine Frenzy
- Season 15 Kate Hudson, Jack Hanna
- Season 15 Colin Farrell, Blake Lively, Lenny Kravitz
- Season 15 Kate Walsh, Jason Sudeikis, OK Go and Bonerama
- Season 15 Evangeline Lilly, Marisa Miller, Brad Paisley
- Season 15 Martin Short, Amy Ryan
- Season 15 Regis Philbin, Joseph Arthur
- Season 15 Charles Barkley, Bill Burr
- Season 15 Dennis Quaid, Ryan Newman, Sharon Jones and the Dap-Kings
- Season 15 Randy Jackson, Saffron Burrows, Ray Davies
- Season 15 Amy Sedaris, Erika Jensen, Foo Fighters
- Season 15 Steve Martin, hand shadows performance with Raymond Crowe
- Season 15 Diddy, Al Lubel
- Season 15 Will Ferrell, Michael McDonald
- Season 15 Courteney Cox, Thomas Friedman, Chingy with Ludacris
- Season 15 Kid Scientists, Natalie Portman, Kenna
- Season 15 Amy Adams, Jamie Oliver, Liam Finn
- Season 15 Woody Harrelson, Tommy Tiernan
- Season 15 Jim Carrey, Paula Abdul
- Season 15 Martha Stewart, Snoop Dogg
- Season 15 Charlize Theron, Lewis Black, British Sea Power
- Season 15 Kate Beckinsale, Graham Colton
- Season 15 Jaime Pressly, Brian Regan
- Season 15 Rainn Wilson, Mike Golic & Mike Greenberg, Bell X1
- Season 15 Al Franken, Lauren Conrad, The Cribs
- Season 15 Brooke Shields, Seth Meyers, Gutter Twins
- Season 15 Demi Moore, Anthony Bourdain, Counting Crows
- Season 15 Kate Bosworth, John Witherspoon, The Raveonettes
- Season 15 Brian Williams, Judy Greer, Langhorne Slim
- Season 15 Helen Mirren, Jose Canseco
- Season 15 Sen. John McCain, Cat Power
- Season 15 George Clooney, Norah Jones
- Season 15 Renee Zellweger, Gayle King, Paddy Casey
- Season 15 Ellen Pompeo, Jay-Z, Mary J. Blige
- Season 15 Al Pacino, David Wright
- Season 15 Kelsey Grammer, Kristen Bell, Rogue Wave
- Season 15 Uma Thurman, Graham Rahal, The Gossip
- Season 15 Kelly Ripa, Dr. John P. Holdren, The Black Keys
- Season 15 Amy Poehler, Jason Segel, Jordan Zevon
- Season 15 Billy Crystal, Maria Sharapova
- Season 15 Helen Hunt, Chris "Mad Dog" Russo, Kathleen Edwards
- Season 15 Danica Patrick, Russell Brand, Tokyo Police Club
- Season 15 Tina Fey, Brett Favre, Estelle
- Season 15 Craig Ferguson, Ira Glass, The Black Crowes
- Season 15 Gwyneth Paltrow, Richard Lewis, The Roots with Chrisette Michele
- Season 15 Robert Downey Jr., Alicia Keys
- Season 15 Matthew Broderick, Heidi Montag, Josh Groban
- Season 15 John Goodman, Bear Grylls, Robyn
- Season 15 Patrick Dempsey, Isabella Rossellini, Nick Lowe
- Season 15 Jimmy Kimmel, Lance Burton, Jimmy Eat World
- Season 15 Ashton Kutcher, Mac King, Steve Winwood
- Season 15 Emile Hirsch, Tom Dreesen, Dirk Arthur
- Season 15 Paris Hilton, Steve Wyrick, Panic at the Disco
- Season 15 Barbara Walters, Cobie Smulders, Penn & Teller
- Season 15 Stupid Pet Tricks, Shia LaBeouf, N.E.R.D.
- Season 15 Regis Philbin, Laura Dern, Death Cab for Cutie
- Season 15 Jack Hanna, Kid Rock
- Season 15 America Ferrera, Russell Brand, Terry Fator
- Season 15 Teri Hatcher, Robert F. Kennedy Jr.
- Season 15 Kevin Spacey, Sen. Jim Webb, Sara Bareilles
- Season 15 Harrison Ford, Ali Lohan, Leona Lewis
- Season 15 Kristin Davis, Jimmy Buffett
- Season 15 Sarah Jessica Parker, Piedmont Bird Callers, Republic Tigers
- Season 15 Liv Tyler, Sue Johanson, Tommy Johnagin
- Season 15 Adam Sandler, Scott Dixon, Donna Summer
- Season 15 Julianne Moore, Morgan Spurlock, a performance from the Broadway musical "South Pacific"
- Season 15 Jack Black, Esperanza Spalding
- Season 15 Julia Roberts, Al Green
- Season 15 Jenna Fischer, Jim Nantz, Gavin Rossdale
- Season 15 Tom Brokaw, Elettra Wiedemann, Gnarls Barkley
- Season 15 Mark Wahlberg, Jeff Peckman, Alanis Morissette
- Season 15 Zooey Deschanel, Scott McClellan, Jakob Dylan
- Season 15 Ben Kingsley, Artie Lange, Emmylou Harris
- Season 15 Whoopi Goldberg , Spencer Pratt, Nick Griffin
- Season 15 Mike Myers, BMX star Kevin Robinson, Adele
- Season 15 Steve Carell, Lance Armstrong, Dr. John
- Season 15 Kevin Garnett & Ray Allen, Jane Krakowski, Martha Wainwright
- Season 15 Jason Bateman, Teri Garr, Keyshia Cole
- Season 15 Denis Leary, The Baseball Project
- Season 15 Will Smith, Joe Buck
- Season 15 Charlize Theron, Richard Belzer, Mötley Crüe
- Season 15 Abigail Breslin, Barry Sonnenfeld, Tift Merritt
- Season 15 Mary-Kate Olsen, Jim Gaffigan, Gavin DeGraw
- Season 15 Morgan Freeman, Kaley Cuoco, Wild Sweet Orange
- Season 15 Pierce Brosnan, Bud Selig, Jason Mraz
- Season 15 Meryl Streep, Aaron Eckhart, Randy Travis
- Season 15 Maggie Gyllenhaal, Neil Young, The Hold Steady
- Season 15 Ricky Gervais, John Mellencamp
- Season 15 Rosie Perez, David Sedaris
- Season 15 Will Ferrell, Adam Savage & Jamie Hyneman
- Season 15 Amanda Peet, Jon Hamm, Augustana
- Season 15 John C. Reilly, Jane Mayer, Grizzly Bear
- Season 15 David Duchovny, Black Kids
- Season 15 Nathan Lane, Larry "Bubbles" Brown, Randy Bachman
- Season 15 Gillian Anderson, Simon Pegg, We Are Scientists
- Season 15 Kevin Costner, Bob Sarlatte, Low vs. Diamond
- Season 15 Pamela Anderson, James Franco, Atmosphere
- Season 15 Luke Wilson, Mindy Kaling, Michael Lauziere
- Season 15 Richard Simmons, Mary-Louise Parker
- Season 15 Seth Rogen, Fleet Foxes
- Season 15 Kelly Ripa, Steve Coogan, Spiritualized
- Season 15 Penelope Cruz, Danny Way, Randy Newman
- Season 15 Kiefer Sutherland, Rumer Willis, Phil Vassar
- Season 15 Donald Trump, Dwayne Kennedy
- Season 15 Shawn Johnson, Tracy Morgan, Solange
- Season 15 Bryan Clay, Don Cheadle, Little Anthony & The Imperials
- Season 15 Kerri Walsh & Misty May-Treanor, Neil Patrick Harris, Nas
- Season 15 Brad Garrett, Blake Lively, Randy Houser
- Season 15 Amy Sedaris, Kim Kardashian, Brian Regan
Late Show with David Letterman - Season 15 Episode 47 Diane Keaton, Jim Gaffigan
6.30 63 minutes Dave begs Gaines to stop feeding in phone calls from the California Highway Patrol, which interrupts the show three times. Also, in her first Letterman appearance in two decades, Diane Keaton kisses Dave and admits to being astounded by her costars in the movie Mad Money.
