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- Season 1 1993-08-30
- Season 2 1994-08-29
- Season 3 1995-09-04
- Season 4 1996-09-02
- Season 5 1997-09-01
- Season 6 1998-08-31
- Season 7 1999-09-07
- Season 8 2000-08-21
- Season 9 2001-08-20
- Season 10 2002-09-03
- Season 11 2003-09-01
- Season 12 2004-08-23
- Season 13 2005-08-29
- Season 14 2006-08-28
- Season 15 2007-09-04
- Season 16 2008-09-02
- Season 17 2009-08-31
- Season 18 2011-01-03
- Season 19 2012-01-03
- Season 20 2013-01-02
- Season 21 2014-01-06
- Season 22 2014-09-02
Season 22 Episode
- Season 19 Will Arnett, Lisa Lampanelli, Guided by Voices
- Season 19 Brian Williams, WU LYF
- Season 19 Tina Fey, Jeremy Irvine, Barr Brothers
- Season 19 Kristen Bell, Dan Naturman, Blind Pilot
- Season 19 Mark Wahlberg, Heather Morris, Snow Patrol
- Season 19 Kate Beckinsale, Marv Albert, The Little Willies
- Season 19 Dolly Parton, Alan Zweibel
- Season 19 Sen. John McCain, Johnny Winter
- Season 19 Viggo Mortensen, Dennis Regan, Tony Bennett
- Season 19 Simon Baker, Elizabeth Banks, Seal
- Season 19 Ricky Gervais, Jessica Chastain, Kathleen Edwards
- Season 19 Marg Helgenberger, Michael Fassbender, Ellie Goulding
- Season 19 Kathy Griffin, Simon Helberg, Joseph Arthur
- Season 19 Dana Carvey, Jon Fisch, Los Campesinos!
- Season 19 Jennifer Lopez, Rob Schneider, James McCartney
- Season 19 Bill Murray, Girls' Generation
- Season 19 Howard Stern, The Airborne Toxic Event
- Season 19 Woody Harrelson, Stephen Merchant, Lana Del Rey
- Season 19 Michelle Williams, Jake Johannsen, Ziggy Marley
- Season 19 Eli Manning, Sarah Michelle Gellar, Die Antwoord
- Season 19 Denzel Washington, The Fray
- Season 19 Ryan Reynolds, Ellie Kemper, Dierks Bentley
- Season 19 Nicolas Cage, Michelle Dockery, The Kills
- Season 19 David Spade, Betty Wright
- Season 19 Reese Witherspoon, Michael Weatherly, Top Ten by Sports Illustrated Swimsuit models, Kasabian
- Season 19 Viola Davis, the 2012 Sports Illustrated Swimsuit cover model, Mark Ronson, Erykah Badu, The Dap-Kings, Zigaboo Modeliste
- Season 19 Jon Stewart, American Bagging Champion Stephanie Teteak, Yelawolf with Kid Rock
- Season 19 Joan Rivers, Andrew Lincoln, Jason Mraz
- Season 19 Kristen Wiig, Mike Birbiglia, Butch Walker and the Black Widows
- Season 19 Jack Hanna, Jesse Tyler Ferguson
- Season 19 Alec Baldwin, Eric Hutchinson
- Season 19 Paul Rudd, John Witherspoon, Heartless Bastards
- Season 19 Kristin Chenoweth, Joe Scarborough, K'naan featuring Nelly Furtado
- Season 19 Matthew Broderick, Nick Griffin, We Are Augustines
- Season 19 Ed Helms, Dan Patrick, Lyle Lovett
- Season 19 Nathan Lane, Pauley Perrette, Estelle
- Season 19 Neil Patrick Harris, Taylor Kitsch, Robert Glasper Experiment featuring Lupe Fiasco & Bilal
- Season 19 Jon Hamm, Ted Alexandro, White Rabbits
- Season 19 Will Ferrell, Jon Bernthal
- Season 19 Amanda Peet, Nick Offerman, Top Ten by Cee-Lo Green, The Chieftains with the Low Anthem
- Season 19 Martin Short, The Ting Tings
- Season 19 Michelle Obama, Esperanza Spalding
- Season 19 Jennifer Lawrence, Gail Collins, The Shins
- Season 19 Debra Messing, Josh Hutcherson, Oberhofer
- Season 19 Rachel Maddow, Timothy Olyphant, Train
- Season 19 Jason Sudeikis, Lionel Richie, Jason Aldean
- Season 19 Chris Elliott, Mohamed Nasheed, Justin Townes Earle
- Season 19 Tracy Morgan, Jim Rome, The Broadway musical 'Once'
- Season 19 Megan Mullally, Joe Wong, Band of Skulls
- Season 19 Keith Olbermann, Allison Williams, Lukas Nelson & Promise of the Real
- Season 19 Kiefer Sutherland, Eugene Levy, The Punch Brothers
- Season 19 Ricky Gervais, Cobie Smulders, Tennis
- Season 19 Sean Hayes, Shooter Jennings
- Season 19 Magic Johnson, Larry Bird, Jim Gaffigan, Kaiser Chiefs
- Season 19 Billy Crystal, Alabama Shakes
- Season 19 Julia Louis-Dreyfus, Keith Alberstadt, Bonnie Raitt
- Season 19 Jason Segel, Zach Wahls, Fun
- Season 19 Amy Poehler, Wendy Williams, Trampled by Turtles
- Season 19 Rob Lowe, Gov. Brian Schweitzer, The War on Drugs
- Season 19 Robin Williams, Andrew Luck
- Season 19 Madden NFL 13 Cover Calvin Johnson, Chris Hemsworth, Darrell Hammond, Miike Snow
- Season 19 Don Rickles, Carrie Underwood
- Season 19 Seth Meyers, Krysten Ritter, Father John Misty
- Season 19 Stupid Pet Tricks, Johnny Galecki, Norah Jones
- Season 19 Stephen Colbert, Chloe Grace Moretz, The cast of 'Nice Work If You Can Get It'
- Season 19 Anderson Cooper, Yves Rossy, Electric Guest
- Season 19 Dr. Phil McGraw, Beth Behrs, Spiritualized
- Season 19 Jim Parsons, Mika Brzezinski, Macy Gray
- Season 19 Eva Longoria, Tom Dreesen, Florence and The Machine
- Season 19 Kid Scientists, Elizabeth Banks, Edward Sharpe & The Magnetic Zeros
- Season 19 Jon Cryer, Tommy Johnagin, M. Ward
- Season 19 Kelly Ripa, Adam Scott, Tenacious D
- Season 19 Brian Williams, El-P
- Season 19 Betty White, Moses Maddox, Best Coast
- Season 19 Conan O'Brien, Regina Spektor, John Mayer
- Season 19 Sacha Baron Cohen, Julie Chen, Beach House
- Season 19 Lea Michele, Barry Sonnenfeld, Shaolin Warriors of Ringling Bros
- Season 19 Will Smith, Gossip
- Season 19 Piedmont Bird Callers, Bill O'Reilly, Pitbull
- Season 19 Joan Rivers, Dario Franchitti, Silversun Pickups
- Season 19 Neil Patrick Harris, Noomi Rapace, Alan Jackson
- Season 19 Jane Fonda, Mayor of London Boris Johnson, Jimmy Cliff
- Season 19 Bill Murray, The Temper Trap
- Season 19 Mark Wahlberg, Sebastian Vettel, Black Box Revelation
- Season 19 Jack Hanna, Patti Smith
- Season 19 Adam Sandler, Jerry Douglas
- Season 19 Regis Philbin, Lenny Marcus, Elizabeth Cook
- Season 19 Denis Leary, Olivia Wilde, The Pierces
- Season 19 Jeff Daniels, Benjamin Walker, Walk the Moon
- Season 19 Alec Baldwin, Michael Kiwanuka
- Season 19 Justin Bieber, Michael Ian Black
- Season 19 Emma Stone, Jimmie Walker, Diamond Rugs
- Season 19 LeBron James, Andrew Garfield, Maroon 5
- Season 19 Channing Tatum, Scott Pelley, The Gaslight Anthem
- Season 19 Blake Lively, Drew Brees
- Season 19 Ray Romano, Tom Waits, Top Ten by American League All-Stars
- Season 19 Queen Latifah, Fred Armisen, Cory Chisel and the Wandering Sons
- Season 19 Bryan Cranston, R.A. Dickey, Zac Brown Band
- Season 19 Anne Hathaway, Moody McCarthy, Loudon Wainwright III
- Season 19 Morgan Freeman, Gallagher, Nas
- Season 19 Roseanne Barr, Aubrey Plaza, Jeff the Brotherhood
- Season 19 Kyra Sedgwick, Mike Golic and Greenberg, Red Wanting Blue
- Season 19 Woody Harrelson, Todd Barry, Grafitti6
- Season 19 Will Ferrell, Rufus Wainwright
- Season 19 Zach Galifianakis, Former U.S. Army Sgt. Valerie Brown, Allen Stone
- Season 19 Jonah Hill, Dr. Leonard Girardi, Milo Greene
- Season 19 Joel McHale, Andrew Norelli, Will.I.Am
- Season 19 Andy Samberg, Ashton Eaton, Glen Hansard
- Season 19 Jennifer Garner, The U.S. Women's Olympic Gymnastics team, Rodriguez
- Season 19 Tom Brokaw, Dana Vollmer, Beth Orton
- Season 19 Tracy Morgan, Erik Kynard, Ben Howard
- Season 19 Kelsey Grammer, Olivia Munn, Train
- Season 19 Bill Hader, Mary-Louise Parker, The Walkmen
- Season 19 Rachel Maddow, Serena Williams, Elle King
- Season 19 Kathy Griffin, Michael Somerville, Josh Turner
- Season 19 Jake Gyllenhaal, Sharon Osbourne, Neon Trees
- Season 19 Amy Adams, Paul Teutul Sr. & Paul Teutul Jr., Hacienda
- Season 19 Michelle Obama, The Chevin
- Season 19 Bruce Willis, Brian Regan, The Heavy
- Season 19 Claire Danes, Dwyane Wade, Bob Mould
- Season 19 Emma Watson, Julie Chen, Matchbox Twenty
- Season 19 Howard Stern, Jason Aldean
- Season 19 Joseph Gordon Levitt, Mindy Kaling, Of Gentlemen and Cowards
- Season 19 President Barack Obama
- Season 19 Michael Strahan, Arthur Meyer
- Season 19 Nathan Lane, Ryan Hunter-Reay, The Killers
- Season 19 Steve Martin, Gotye
- Season 19 Stupid Human Tricks, Kaley Cuoco, The Whigs
- Season 19 David Cameron, Jonny Lee Miller
- Season 19 Jimmy Fallon, Neil Young, Lupe Fiasco
- Season 19 Regis Philbin, Tom Dreesen, Dwight Yoakam
- Season 19 Stephen Colbert, Theresa Caputo, Martha Wash
- Season 19 Martin Short, Kat Dennings
- Season 19 Tina Fey, Rick Santorum, LP
- Season 19 Craig Ferguson, Anna Kendrick, The Raveonettes
- Season 19 Billy Crystal, The Wallflowers
- Season 19 Jack Hanna, Max Greenfield
- Season 19 Kevin James, Chris Elliott, Miguel
- Season 19 Salma Hayek Pinault, Nick Offerman, KISS
- Season 19 Lucy Liu; Rob Corddry; Daughter
- Season 19 John Goodman, Jeff Altman, Jamey Johnson with Alison Krauss
- Season 19 Tom Hanks; Tony Bennett
- Season 19 Taylor Swift; Rachel Maddow
- Season 19 Bill O'Reilly; Nicole Snooki Polizzi; The Lumineers
- Season 19 Donald Trump; Adam Levine; Carly Rae Jepsen
- Season 19 Dennis Quaid; Krysten Ritter; Diamond Rings
- Season 19 Denzel Washington, Paul Banks
- Season 19 Jim Cantore; Ken Burns; Andrew Bird
- Season 19 Katie Couric; Rita Ora
- Season 19 Steven Tyler and Joe Perry; Judy Greer; Aerosmith
- Season 19 Jason Sudeikis; Michael Che; Ultraĩsta
- Season 19 Ricky Gervais; Simon Helberg; Ty Segall
- Season 19 Brian Williams; Ne-Yo
- Season 19 Robin Williams; Lianne La Havas
- Season 19 Anderson Cooper; Myq Kaplan; Alberta Cross
- Season 19 Bradley Cooper; Robert Klein; Soundgarden
- Season 19 Julianna Margulies; Mumford & Sons
- Season 19 Alec Baldwin; Dirty Projectors
- Season 19 Zooey Deschanel; Lisa Lampanelli; Donald Fagen
- Season 19 Dr. Phil McGraw; Carmen Lynch; Divine Fits
- Season 19 Jessica Biel; Pete Townshend; Philip Phillips
- Season 19 Amy Poehler; Josh Hutcherson; Tegan and Sara
- Season 19 Scarlett Johansson; Willie Nelson; Gary Clark Jr.
- Season 19 Led Zeppelin; John Krasinski; Paloma Faith
- Season 19 Matt Damon; Martin Freeman; JD McPherson
- Season 19 Albert Brooks; Diana Krall
- Season 19 Bill Murray; Vintage Trouble
- Season 19 Dustin Hoffman; One Direction
- Season 19 Anne Hathaway; Jake Johnson; “The President's Own” United States Marine Band
- Season 19 Amanda Seyfried; Natalia Makarova; Awolnation
- Season 19 Billy Crystal; James Balong; Grizzly Bear
- Season 19 Jamie Foxx; Julie Chen; DIIV
- Season 19 Samuel L. Jackson; Carrie Brownstein & Fred Armisen; Jason Isbell and the 400 Unit
- Season 19 Tom Cruise; MNDR
- Season 19 Paul Rudd; Alicia Keys
- Season 19 Seth Rogen; John Witherspoon
- Season 19 Katie Holmes; Jon Bon Jovi
- Season 19 Naomi Watts; Jay Thomas; Darlene Love
Late Show with David Letterman - Season 19 Episode 12 Marg Helgenberger, Michael Fassbender, Ellie Goulding
6.26 63 minutes Dave welcomes actress Marg Helgenberger from the CBS drama series "CSI: Crime Scene Investigation," actor Michael Fassbender, and musical guest Ellie Goulding.
