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- Season 1 1993-08-30
- Season 2 1994-08-29
- Season 3 1995-09-04
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- Season 5 1997-09-01
- Season 6 1998-08-31
- Season 7 1999-09-07
- Season 8 2000-08-21
- Season 9 2001-08-20
- Season 10 2002-09-03
- Season 11 2003-09-01
- Season 12 2004-08-23
- Season 13 2005-08-29
- Season 14 2006-08-28
- Season 15 2007-09-04
- Season 16 2008-09-02
- Season 17 2009-08-31
- Season 18 2011-01-03
- Season 19 2012-01-03
- Season 20 2013-01-02
- Season 21 2014-01-06
- Season 22 2014-09-02
Season 22 Episode
- Season 4 Chuck Norris, Anthony Clark, Jewel
- Season 4 Mira Sorvino, Vincent Perez, Beck
- Season 4 Whoopi Goldberg, Al Franken, Colonel Ron Severson
- Season 4 Adam Sandler, David Cone, LeAnn Rimes
- Season 4 Bill Cosby, Brian Williams, No Doubt
- Season 4 Jamie Lee Curtis, Pete Sampras, John Mellencamp
- Season 4 Jon Stewart, Marv Albert, Cranberries
- Season 4 Cybill Sheperd, Carl Coccilone, Ray Romano
- Season 4 Tom Brokaw, Natasha Henstridge, Fan Yang
- Season 4 John McEnroe, Illeana Douglas, 311
- Season 4 Tim Allen, Tyson Koenig, Suzanne Vega
- Season 4 Fran Drescher, Jesse Jackson, Travis Tritt
- Season 4 Bill Cosby, Kin-Jin Mark, A Tribe Called Quest
- Season 4 Goldie Hawn, Louie C.K.
- Season 4 Stupid Pet Tricks, Drew Barrymore, Tony Avena, Pearl Jam
- Season 4 Sarah Jessica Parker, Andy Richter, Darrell Hammond
- Season 4 Ellen DeGeneres, Stephen King, Trisha Yearwood
- Season 4 William Baldwin, Jeff Gordon, Vince Gill
- Season 4 Hugh Grant, Elizabeth Berkley, Donna Lewis
- Season 4 Kirstie Alley, Matthew Broderick
- Season 4 Ricki Lake, Gillian Anderson, Tom Petty & the Heartbreakers
- Season 4 Tom Hanks, Gina Gershon, Riverdance
- Season 4 Val Kilmer, Nicole Sullivan, ZZ Top
- Season 4 Julie Andrews, "Pee Wee" Scheidt, Dave Matthews Band
- Season 4 Wayne Gretzky, Jonathan Silverman, Tori Amos
- Season 4 Michael J. Fox, Jeanne Moreau, Ray Davies
- Season 4 Sam Donaldson, Spike Lee, Clint Black
- Season 4 Samuel L. Jackson, Leela Rashon, Midnight Oil
- Season 4 Geena Davis, Peter Gallagher, Andy Kindler
- Season 4 George Foreman, Tom Everett Scott, Shawn Colvin
- Season 4 Cindy Crawford, Jack Hanna, Lyle Lovett
- Season 4 Rosie O'Donnell, Jon Favreau, Sheryl Crow
- Season 4 Jon Lovitz, Ken Olin, Enrique Iglesias
- Season 4 Ted Danson, Claire Danes, Phil Collins
- Season 4 Jimmy Smits, John Leguizamo, Brian Regan
- Season 4 Joe Torre, Don Rickles, The Heads
- Season 4 George Steinbrenner, Jeremy Piven, Chris Isaak
- Season 4 Isabella Rossellini, Garry Marshall, Bryn Terfel
- Season 4 Jeff Foxworthy, Naomi Campbell, Jake Johannsen
- Season 4 Stupid Human Tricks, Dana Carvey, Steven Wright
- Season 4 Mel Gibson, Christine Lahti, Joni Mitchell
- Season 4 Marisa Tomei, James Carville, John Michael Montgomery
- Season 4 Brett Butler, Gary Sinise, Bob McCoy
- Season 4 Bob Dole, Ted Koppel, Mary Chapin Carpenter
- Season 4 Jeff Bridges, Diane Sawyer, Bryan White
- Season 4 Marilu Henner, Kristin Scott Thomas, Alan Jackson
- Season 4 Ron Howard, Patrick Ewing, Gene Catron
- Season 4 Tony Randall, Wendy Liebman, Helena Bonham Carter
- Season 4 Stupid Pet Tricks, Anthony Edwards, Natalie Cole
- Season 4 Sarah Ferguson, Derek Jeter, Reba McEntire
- Season 4 Heather Locklear, Sinbad, Tony Toni Tone
- Season 4 Glenn Close, Marc Maron, Eriq LaSalle
- Season 4 Phil Hartman, Bob Costas, Luther Vandross
- Season 4 Kid Inventors, Will Smith, Jimmy Buffett
- Season 4 Lisa Kudrow, Delroy Lindo, Wynonna
- Season 4 Jeff Daniels, Dolly Parton
- Season 4 Martin Short, Scott Bryan, Rita Wilson
- Season 4 Lea Thompson, Natalie Portman, Stone Temple Pilots
- Season 4 Teri Hatcher, Brent Spiner, Luscious Jackson
- Season 4 John Cleese, Martha Stewart, David Copperfield
- Season 4 Nicole Kidman, Laura Dern, Gloria Estefan
- Season 4 Kenneth Branaugh, Bonnie Hunt, Counting Crows
- Season 4 James Woods, Bob Odenkirk, Counting Crows
- Season 4 Albert Brooks, Beavis & Butthead, Neil Diamond
- Season 4 Drew Barrymore, Mathias Pakula, Faith Hill
- Season 4 Andie MacDowell, Jimmie Walker, Rhett Atkins
- Season 4 Harry Connick Jr., Walter Cronkite
- Season 4 Richard Simmons, Neve Campbell, Dave Matthews Band
- Season 4 Billy Crystal, Cuba Gooding Jr., Darlene Love
- Season 4 John Travolta, Julianna Marguiles, St. Luke's Bottle Band
- Season 4 Nathan Lane, Kelly Preston, Rich Hall
- Season 4 Jane Pauley, Robert Pastorelli, Blues Traveler
- Season 4 Mary Tyler Moore, Jerry O'Connell, Oseola McCarty, Deana Carter
- Season 4 Tom Arnold, Kamarr, Joe Queenan
- Season 4 Alec Baldwin, Cast of Chicago
- Season 4 Courtney Cox, Lee Marek, Damon Hill
- Season 4 Kids Tell Jokes, Tracey Ullman, B.B. King
- Season 4 Ray Liotta, Norm MacDonald
- Season 4 Woody Harrelson, Jackie Chan, John Pizzarelli
- Season 4 Matt Dillon, Rebecca Ramijn, Cassandra Wilson
- Season 4 Eddie Murphy, Dwight Yoakam, Veronica Paridee
- Season 4 Kevin Spacey, Madeline Kahn, Harry Hill
- Season 4 Penelope Ann Miller, Skeet Ulrich, BR5-49
- Season 4 Chris O'Donnell, Debbie Reynolds, Yo Yo Ma, Edgar Meyer, Mark O'Conner
- Season 4 Tom Selleck, Art Donovan, Babyface
- Season 4 Kevin Kline, Kevin Sorbo, Kevin Brennan
- Season 4 David Schwimmer, Carmen Electra, Sheryl Crow
- Season 4 Tony Danza, Desmond Howard, Helena Bonham Carter
- Season 4 Dan Rather, Jane Leeves, Tori Amos
- Season 4 Matthew Perry, Natasha Lyonne, Jewel
- Season 4 Rhea Perlman, Ray Ramano, Ice Cube
- Season 4 Stupid Human Tricks, Elle MacPherson, Charles Barkley
- Season 4 Isabella Rossellini, Billy Bob Thorton, Tokyo Shock Boys
- Season 4 Fran Drescher, Eva Herzigova, Tony Bennett
- Season 4 Pierce Brosnan, Lance Alstodt, Brian Regan
- Season 4 Brett Favre, David Spade, Silverchair
- Season 4 Stupid Pet Tricks, Brett Butler, Fugees
- Season 4 Sarah Jessica Parker, Geoffrey Rush, Barry Manilow
- Season 4 Richard Harris, Siskel & Ebert, Far East Circus
- Season 4 Peter O'Toole, Salma Hayek, Jazz Passengers
- Season 4 Sarah Ferguson, Allan Weimerskirch, Patti Smith
- Season 4 Tom Brokaw, Laura Linney, BLACKstreet
- Season 4 Bruce Willis, Ving Rhames, Jeff Gordon
- Season 4 Michael J. Fox, Jon Voight, The Wallflowers
- Season 4 Julie Andrews, Doug E. Doug, The Amazing Jonathan
- Season 4 Tony Randall, Juliette Binoche, David Brenner
- Season 4 Bill Cosby, David Hacker, Tina Turner
- Season 4 Mia Farrow, Anne Heche, Elvis Costello & Burt Bacharach
- Season 4 Howard Stern, Valeria Mazza, Porno for Pyros
- Season 4 Pauly Shore, Merrill Markoe, Celine Dion
- Season 4 Bill Pullman, Richard Lewis, Lyle Lovett & Randy Newman
- Season 4 Jon Stewart, Debi Mazar, Duncan Sheik
- Season 4 Robin Quivers, Adam Arkin, James
- Season 4 Chevy Chase, Mary McCormack, Phish
- Season 4 Kids Tell Jokes, Mary Steenburgen, Ray Wold
- Season 4 Ted Danson, Famke Janssen, Mitch Hedburg
- Season 4 Howard Stern, Ray Ramano, Chieftains
- Season 4 Martin Short, Larenz Tate, Kodo
- Season 4 Cindy Crawford, Robert Townsend, Chris Whitley
- Season 4 Mike Myers, Sophie Marceau, Alison Krauss
- Season 4 Marv Albert, Anthony LaPaglia, Big Head Todd & the Monsters
- Season 4 Teri Garr, George Stephanopolous, Amanda Marshall
- Season 4 Marilu Henner, Marlon Wayans, The Cardigans
- Season 4 Bryant Gumbel, Kadeem Hardison, Bandbaz Brothers
- Season 4 Tara Lipinsky, Margaret Colin, Nanci Griffith
- Season 4 Dan Akroyd, David Kruithoff, Cyndi Lauper
- Season 4 Jean-Claude Van Damme, Brad Garrett, Chris Fonseca
- Season 4 John Cusak, Liv Tyler, David Bowie
- Season 4 Anthony Clark, Joan Lunden, Eryka Badu
- Season 4 Norm MacDonald, Justine Bateman, Trace Adkins
- Season 4 Charles Grodin, David Alan Grier, Matthew Sweet
- Season 4 Tom Arnold, Bernie Williams, Bush
- Season 4 Kelsey Grammar, Jake Johannsen, Tracy Chapman
- Season 4 Martin Mull, Alicia Witt, Mary J. Blige
- Season 4 Katie Couric, Roma Downey, INXS
- Season 4 Tony Randall, Steven Weber, Wilco
- Season 4 Lisa Kudrow, Umberto Buccigrossi, Verve Pipe
- Season 4 Stupid Human Tricks, Rosie Perez, John Hiatt
- Season 4 Kurt Russell, Sinbad, Paula Cole
- Season 4 Robin Williams, Tanya Tucker
- Season 4 Alec Baldwin, Joey Lauren Adams, Indigo Girls
- Season 4 Garry Shandling, Luke Perry, Wendy Liebman
- Season 4 Roseanne, Justin Miller, Chuck Berry
- Season 4 Bruce Willis, Elizabeth Hurley, Maxwell
- Season 4 John Goodman, Kathleen Quinlan, Hanson
- Season 4 Mike Myers, Danny Aiello, Crossbows of Death
- Season 4 Billy Crystal, Kristen Johnson, Bee Gees
- Season 4 Ricki Lake, Kirby Puckett, Soul Asylum
- Season 4 Cybil Shepard, Darrell Hammond, Linda Eder
- Season 4 Andy Garcia, George Foreman, Travis Tritt
- Season 4 David Hyde Pierce, Dana Delany, Spice Girls
- Season 4 Helen Hunt, Susie Maroney, Jeffery Tambor
- Season 4 Stupid Pet Tricks, Jeff Goldblum, Foo Fighters
- Season 4 Meg Ryan, Lance Henriksen, Mary Chapin-Carpenter
- Season 4 Barbara Walters, Ida Doggett, God's Property with Kirk Franklin
- Season 4 Richard Simmons, Kelly Preston, Toad the Wet Sprocket
- Season 4 Matthew Broderick, Nicole Sullivan, Savion Glover & Stomp
- Season 4 Jason Alexander, Griffin Dunne, Sammy Hagar
- Season 4 Elle MacPherson, Vince Vaughn, Jewel
- Season 4 Michael Richards, Rick Reynolds, Steve Winwood
- Season 4 Bill Cosby, Elaine Cunningham, Squirrel Nut Zippers
- Season 4 Alicia Silverstone, Andy Dick, John Fogerty
- Season 4 Farrah Fawcett, John Fogerty
- Season 4 Harrison Ford, Steven Wright, Dave Matthews Band
- Season 4 Isabella Rossellini, Dave Chapelle, Bono & Larry Mullen
- Season 4 Jon Stewart, Susan Molinari, Seven Mary Three
- Season 4 Tom Brokaw, Janeane Garafolo, Sheryl Crow
- Season 4 John Travolta, Grant Hill, Sinead O'Connor
- Season 4 George Carlin, Nick Chinlund, James Taylor
- Season 4 Kathy Ireland, Jeremy Holz, Michael Story
- Season 4 Matt Lauer, Ruthie Bolton-Holifield, Mighty Mighty Bosstones
- Season 4 Julia Roberts, Jon Bon Jovi
- Season 4 Siskel & Ebert, Dermot Mulroney, King Charles Troupe
- Season 4 Marilu Henner, Doug E. Doug, Johnny Lang
- Season 4 Nick Turturro, Daisy Fuentes, Motley Crue
- Season 4 Peter Fonda, Jonathan Taylor Thomas, Ricki Lee Jones
- Season 4 Brian Williams, Diane Cannon, Gil Shaham
- Season 4 Martin Lawrence, Robert Zemeckis, Sarah McLachlan
- Season 4 Will Smith, Heidi Klum, Brad Byers
- Season 4 Jason Priestly, Patricia Richardson, The Cicadas
- Season 4 Tom Arnold, Mitchell Libonati, Blur
- Season 4 Evander Holyfield, Lee Marek, Sarah Silverman
- Season 4 Martin Short, Manny the Hippie, Fang Fang
- Season 4 Don Rickles, Brendan Fraser, En Vogue
- Season 4 Tim Robbins, Jackie Chan, Shawn Colvin
- Season 4 Mary Tyler Moore, Querbe Tirmizi, Matchbox 20
- Season 4 Nathan Lane, Robey Morgan, Third Eye Blind
- Season 4 Robert Pastorelli, Craig Kilborn, Live
- Season 4 Pauly Shore, Leslie Mann, Puff Daddy
- Season 4 Kids Tell Jokes, Mario Andretti, John Hiatt
- Season 4 John Turturro, Kathy Kinney, Radish
- Season 4 Dan Rather, Kathy Griffin, k.d. Lang
- Season 4 Samuel L. Jackson, Barry Sonnenfeld
- Season 4 Jennifer Anniston, Brian Regan, William H. Macy
- Season 4 Norm MacDonald, Phylicia Rashad, Jamiroquai
- Season 4 Charles Grodin, Billy Connolly, David Byrne
- Season 4 Julia Roberts, Blues Traveler
- Season 4 Tony Danza, Michael Rapaport
- Season 4 Bob Dole, Bill Bellamy, Ziggy Marley & the Melody Makers
- Season 4 Ray Liotta, David Brenner, Natalie Desselle
- Season 4 Jay Thomas, Annabella Sciorra, Tonic
- Season 4 Sylvester Stallone, Tommy LaSorda
- Season 4 Demi Moore, Jay Mohr, Aerosmith
- Season 4 Tom Selleck, Billy Joel
- Season 4 Barbara Walters, Charles Dutton, Morrissey
- Season 4 Mira Sorvino, Jeff Altman, Coolio
- Season 4 Donald Trump, Janine Turner, Ruth Brown & Bonnie Raitt
- Season 4 Alicia Silverstone, Bev Tanner, George Miller
- Season 4 Vanessa Williams, Joe Montana
- Season 4 Paul Reiser, Tia Carrera, Echo & the Bunnymen
- Season 4 Laurence Fishburne, Jonathan Katz, Paula Cole
- Season 4 Tom Arnold, Mehgan Heany-Grear, Dane Cook
- Season 4 Stupid Human Tricks, Danny Aiello, Radiohead
Late Show with David Letterman - Season 4 Episode 143 Roseanne, Justin Miller, Chuck Berry
6.26 63 minutes In honor of tonight's audience (all residents of St. Louis and its suburbs), the backdrop is altered to show the city's skyline; Dave shows live footage of the Mets/Cardinals game in progress at Shea Stadium; Roseanne arrives for her interview on a Clydesdale-driven sleigh.
