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- Season 1 1993-08-30
- Season 2 1994-08-29
- Season 3 1995-09-04
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- Season 5 1997-09-01
- Season 6 1998-08-31
- Season 7 1999-09-07
- Season 8 2000-08-21
- Season 9 2001-08-20
- Season 10 2002-09-03
- Season 11 2003-09-01
- Season 12 2004-08-23
- Season 13 2005-08-29
- Season 14 2006-08-28
- Season 15 2007-09-04
- Season 16 2008-09-02
- Season 17 2009-08-31
- Season 18 2011-01-03
- Season 19 2012-01-03
- Season 20 2013-01-02
- Season 21 2014-01-06
- Season 22 2014-09-02
Season 22 Episode
- Season 14 Andy Kindler, motocross demo with Travis Pastrana, Baby Gramps
- Season 14 Zach Braff, Jeff Brendenburg, The Roots
- Season 14 Snoop Dogg, Charlie Hill, OK Go
- Season 14 Julianne Moore, radio-show hosts Opie and Anthony
- Season 14 Al Franken, Todd Snider
- Season 14 Maria Sharapova, Martha Stewart, Justin Timberlake
- Season 14 Ashton Kutcher, Sam Hornish, Jr., TV on the Radio
- Season 14 Dwayne "The Rock" Johnson, Norm MacDonald
- Season 14 Anne Heche, Luke Ravenstahl, The Who
- Season 14 Johnny Knoxville, Rachael Ray
- Season 14 Dr. Phil McGraw, Willie Tyler and Lester, Sekou Bunch
- Season 14 Patrick Dempsey, Jay Johnson and Darwin, Kasabian
- Season 14 Marg Helgenberger, Ronn Lucas and Scorch, Diana Krall
- Season 14 Ted Turner, Jeff Dunham and Walter, Fergie
- Season 14 LeBron James, Todd Oliver and Irving, Ludacris
- Season 14 Ray Liotta, Elvis Costello & Tony Bennett, Billy Garcia
- Season 14 Billy Bob Thornton, Lily Capehart, Sean Lennon
- Season 14 Amanda Peet, Nigella Lawson, Bob Seger
- Season 14 Sir Richard Branson, Dane Cook, Monica
- Season 14 Nathan Lane, Jeff Caldwell
- Season 14 Pete Rose, Roy Wood Jr., Cecilia Mansilla
- Season 14 Andy Dick, Keith Olbermann, Brazilian Girls
- Season 14 Alec Baldwin, Vladae the Dog Wizard, Jerry Lee Lewis & Neil Young
- Season 14 Frank Caliendo, Rachael Harris, Xzibit, Phil Pfister
- Season 14 Amy Sedaris, Trey Anastasio
- Season 14 Robin Williams, J.P. Calderon, Sam Moore with Wynonna
- Season 14 Nicky Hilton, Bob Woodward, Joseph Arthur
- Season 14 Jon Stewart, Nick Lachey
- Season 14 Katie Couric, Brian Kiley, Alan Jackson
- Season 14 Diddy, Neil Patrick Harris
- Season 14 Tom Arnold, Brian Regan, the latest "Survivor: Cook Islands" castaway
- Season 14 Tina Fey, Mike Golic & Mike Greenberg, The Killers
- Season 14 Julia Louis-Dreyfus, Jay Thomas, John Legend
- Season 14 Tim Robbins, Gene Rurka, Russell Thompkins Jr. and The New Stylistics
- Season 14 Bill O'Reilly, Jeff Altman, Tilly and the Wall
- Season 14 Borat, Tiki Barber, Beck
- Season 14 Rachel Weisz, David Rakoff, Morningwood
- Season 14 Gary Sinise, Joanne Carson, Jim Norton
- Season 14 Rosie O'Donnell, Lady Sovereign
- Season 14 Martin Short, Kinky Friedman
- Season 14 Will Ferrell, Jack Hanna
- Season 14 Dustin Hoffman, Jamie Oliver, The Metropolitan Opera
- Season 14 Kiefer Sutherland, Jenna Fischer, Rocco DeLuca
- Season 14 Daniel Craig, documentary film subject Teri Horton, Elvis Costello, Rosanne Cash
- Season 14 Robin Williams, Rich Little, George Jones
- Season 14 Jack Black & Kyle Gass, Fred Travalena, Tenacious D
- Season 14 Ellen DeGeneres, Gordie Brown, +44
- Season 14 Christopher Guest, Frank Caliendo, The Game
- Season 14 Sen. John Edwards, Kevin Pollak, Will Arnett
- Season 14 Jerry Seinfeld, Dan Patrick
- Season 14 Hugh Jackman, Chris Elliott, Jimmie Johnson
- Season 14 Matthew Broderick, Lupe Fiasco & Jill Scott
- Season 14 Eugene Levy, John Mayer
- Season 14 Helen Hunt, DJ Shadow, Q-Tip and Lateef
- Season 14 Kate Winslet, Tom Waits
- Season 14 George Clooney, The Decemberists
- Season 14 Richard Simmons, Kate Walsh, Ciara
- Season 14 Jennifer Connelly, Tom Dreesen, Shiny Toy Guns
- Season 14 Danny DeVito, 16-year-old duct tape expert William Beacom, Silversun Pickups
- Season 14 Matt Damon, Barbara Walters
- Season 14 Howard Stern, Gwen Stefani
- Season 14 Kid Scientists, Regis Philbin, Robert Randolph
- Season 14 Will Smith, Evanescence
- Season 14 Clint Eastwood, Matthew Fox
- Season 14 Frank Caliendo as John Madden, Ben Stiller, Rodrigo & Gabriela
- Season 14 Beyonce, Marv Albert, The Dears
- Season 14 Renée Zellweger, holiday toy demonstration, Taking Back Sunday
- Season 14 Tom Brokaw, Cold War Kids
- Season 14 Cate Blanchett, Jay Thomas, Darlene Love
- Season 14 Martin Short, Donal Logue
- Season 14 Matt Lauer, Artie Lange, Augustana
- Season 14 Cedric the Entertainer, Wesley Autrey, Switchfoot
- Season 14 Donald Trump, Mary Lynn Rajskub
- Season 14 David Arquette, Jennifer Hudson
- Season 14 Penelope Cruz, Gary Mule Deer, Ben E. King
- Season 14 Peter O'Toole, Marc Maron
- Season 14 Julianne Moore, Madonna, The Hold Steady
- Season 14 Kristin Chenoweth, John Witherspoon, Josh Ritter
- Season 14 Amy Sedaris, Jason Randal, America with Ryan Adams & Ben Kweller
- Season 14 Paul Newman, Sebastian Bourdais, Diana Ross
- Season 14 Tina Fey, Terri and Bindi Irwin
- Season 14 Harry Shearer, Vera Farmiga, Mat Kearney
- Season 14 Dan Rather, Tricia Helfer, Andy Kindler
- Season 14 Kevin Spacey, Alicia Keys, Nellie McKay & The Brooklyn Philharmonic
- Season 14 Ricky Gervais, Forest Whitaker, The Shins
- Season 14 Frank Caliendo, Mandy Moore, Rosanne Cash
- Season 14 Bill Murray, LeBron James
- Season 14 David Spade, Alexandra Pelosi, Dustin Kensrue
- Season 14 Dr. Phil McGraw, Fall Out Boy
- Season 14 Randy Jackson, Harry Connick Jr., Regis
- Season 14 Chris Elliott, Kelly Ripa, John Mellencamp
- Season 14 Jack Hanna, Katherine Heigl, Patty Griffin
- Season 14 Rachael Ray, Frank Caliendo, The Fab Faux
- Season 14 Drew Barrymore, Rickie Lee Jones, Kevin Johnson with Clyde & Matilda
- Season 14 Peyton Manning, Dan Horn with Orson, The Cat Empire
- Season 14 Martha Stewart, Otto Petersen with George, Norah Jones
- Season 14 Sienna Miller, NAS, Jim Barber with Seville
- Season 14 Tracy Morgan, Gabrielle Union, Brad Cummings and Rex
- Season 14 Jim Carrey, Daytona 500 winner Kevin Harvick
- Season 14 Barbara Walters, David Neeleman, K-os
- Season 14 John Travolta, Eric Nerhus, a performance from the Broadway musical "Spring Awakening"
- Season 14 Billy Bob Thornton, Rashida Jones, Barenaked Ladies
- Season 14 Samuel L. Jackson, Jim Gaffigan
- Season 14 Jake Gyllenhaal, Brand New
- Season 14 Evangeline Lilly, Jeff MacGregor, bubble blowing guy Tom Noddy
- Season 14 Sen. John McCain, Robin Thicke
- Season 14 Bob Woodruff, John Mayer
- Season 14 Charles Grodin, Dan Naturman
- Season 14 Chris Rock, Sandra Oh, Amy Winehouse
- Season 14 Jeff Goldblum, Barbara McQueen
- Season 14 Richard Gere, Explorers Club chef Gene Rurka, Aqualung
- Season 14 Bernie Mac, Paula Abdul, Joss Stone
- Season 14 Adam Sandler, Don Cheadle, Danica Patrick, Todd Barry, Lucinda Williams
- Season 14 Jack Black, Lara Logan, beer launching refrigerator creator John Cornwell
- Season 14 Will Ferrell, Kings of Leon, Rachel Smith
- Season 14 Patricia Arquette, Paul Mooney, Macy Gray
- Season 14 Al Franken, Isla Fisher
- Season 14 Rosario Dawson, Bloc Party, Piedmont bird callers
- Season 14 Donald Trump, Jon Heder
- Season 14 Sen. Barack Obama, Halle Berry, Zach Johnson
- Season 14 David Duchovny, Ryan Howard, Andrew Bird
- Season 14 Alec Baldwin, Debbie Parkhurst and her dog Toby, LCD Soundsystem
- Season 14 Bruce Willis, Jason Randal
- Season 14 Bill Cosby, Angela Kinsey
- Season 14 Kelly Ripa, Simon Pegg
- Season 14 Craig Ferguson, Dave Della Terza, Avril Lavigne
- Season 14 Edie Falco, Paul Scheer, Son Volt
- Season 14 Garry Shandling, Paul Teutul Sr. and Jr., Tokyo Police Club
- Season 14 Jessica Biel, Ira Glass, Regina Spektor
- Season 14 Brian Williams, Steven Wright, a Top Ten list presented by Sanjaya Malakar
- Season 14 David Hyde Pierce, Ivanka Trump, Corinne Bailey Rae
- Season 14 Nicolas Cage, Barry Sonnenfeld, The Fratellis
- Season 14 Steve Martin, Dave Cota and A.J. the parakeet, Derek Jeter
- Season 14 Frank Caliendo as President George W. Bush, Andy Dick, Jarvis Cocker
- Season 14 Kirsten Dunst, Rob Magnotti, Dinosaur Jr.
- Season 14 Tobey Maguire, John Byner, Modest Mouse
- Season 14 Drew Barrymore, Mike MacRae, Ben Kweller
- Season 14 Marcia Cross, Joe Piscopo, Tori Amos
- Season 14 Ray Romano, Reggie Reg, Dennis Haysbert
- Season 14 Regis Philbin, Darlene Love
- Season 14 Jane Fonda, Tom Ruprecht, Kelly Clarkson
- Season 14 Lindsay Lohan, Tom Dreesen, The Kooks
- Season 14 Dr. Phil McGraw, Jack Hanna
- Season 14 Charles Grodin, Jake Johannsen
- Season 14 Mike Myers, America Ferrera
- Season 14 Don Rickles, Michael Imperioli, Wilco, a Top Ten List presented by Masi Oka
- Season 14 Ricky Gervais, Mary Lynn Rajskub, Mavis Staples, a Top Ten List presented by Bob Barker
- Season 14 Kid Scientists, Luke Wilson, Rufus Wainwright, a Top Ten List presented by Homer Simpson
- Season 14 Teri Hatcher, Jonah Hill, Elvis Costello
- Season 14 Rudolph Giuliani, Mike West, Jesus & Mary Chain
- Season 14 Charles Barkley, Seth Rogen, Michael Martin Murphey
- Season 14 Stupid Pet Tricks, Rosie Perez, Dr. Dog
- Season 14 Al Gore, Jim Short
- Season 14 Kevin Spacey, Alexis Bledel
- Season 14 Matt Damon, Indianapolis 500 winner Dario Franchitti, Bright Eyes
- Season 14 Chevy Chase, Amanda Beard, Satellite Party
- Season 14 Nicole Richie, Artie Lange, Chrisette Michele
- Season 14 Amy Sedaris, Chuck "The Iceman" Liddell, Jordan Zevon
- Season 14 Ellen Barkin, Brian Regan
- Season 14 Denis Leary, Flight of the Conchords, Neal Seaver
- Season 14 Kyra Sedgwick, Sir Richard Branson, Maroon 5
- Season 14 Bear Grylls, Jeremy Piven, Elvis Perkins
- Season 14 John Cusack, Pink Martini, Turkey Gobbling Champions
- Season 14 Michael Moore, Bill Burr
- Season 14 Bruce Willis, Tony Parker, diving dogs
- Season 14 Amanda Peet, John Krasinski, Bryan Ferry
- Season 14 Claire Danes, Dan Patrick & Keith Olbermann, Ryan Adams & The Cardinals
- Season 14 Robin Williams, Julie Chen
- Season 14 Dennis Kucinich, Shia LaBeouf, Morrissey
- Season 14 Don Cheadle, Smashing Pumpkins, Venus Williams
- Season 14 Sienna Miller, Michael Cera, Interpol
- Season 14 Diddy, Emma Watson, Spoon
- Season 14 Paul Teutul Sr. and Jr., Vera Farmiga, Joe Matarese
- Season 14 Queen Latifah, Alan Zweibel, Smashing Pumpkins
- Season 14 Michelle Pfeiffer, Jonah Hill, Michel Lauziere
- Season 14 Adam Sandler, Mike Golic and Mike Greenberg, Mute Math
- Season 14 John Travolta, Paula Abdul, Teddy Thompson
- Season 14 Kevin James, Jose Andres, White Rabbits
- Season 14 Julia Stiles, Pete Jordan, Nick Griffin
- Season 14 Drew Carey, Nikki Blonsky, Grinderman
- Season 14 Paul Rudd, Tony Dungy, The National
- Season 14 Catherine Zeta-Jones, Bob Sarlatte, Porter Wagoner
- Season 14 Sharon Osbourne, Brian Kiley, Yeah Yeah Yeahs
- Season 14 Anne Hathaway, Jim Gaffigan, Buffalo Tom
- Season 14 Andy Samberg, Catherine Bell, The Bravery
- Season 14 Sen. Joe Biden, Seth Rogen, Gogol Bordello
- Season 14 Matt Damon, Jeff Altman, Angelique Kidjo
- Season 14 Jackie Chan, Chelsea Handler, Michael Buble
- Season 14 Glenn Close, Judd Apatow, Chris & Rich Robinson
- Season 14 Jeff Goldblum, Hayden Panettiere, New Pornographers
- Season 14 Samuel L. Jackson, Christiane Amanpour, Tom Russell
- Season 14 Richard Gere, Tom Dreesen, Velvet Revolver
- Season 14 Tina Fey, Venus Williams, Steve Earle
- Season 14 Tom Arnold, Kristin Gore, Jim McDonald
- Season 14 Susan Sarandon, Rick Reilly, Feist
- Season 14 Kevin Bacon, Kat Von D, T.I. with Wyclef
- Season 14 Ellen DeGeneres, Jeff Garlin, Against Me!
- Season 14 Sen. Hillary Rodham Clinton, Willie Nelson & Kenny Chesney
- Season 14 Amy Sedaris, Will Arnett
Late Show with David Letterman - Season 14 Episode 114 Jack Black, Lara Logan, beer launching refrigerator creator John Cornwell
6.26 63 minutes Tonight's "Great Moments in Presidental Speeches" clip is doctored to include Sue Hum using a lint brush on JFK's right arm; Duke University post-grad John Cornwell demonstrates his new invention, the beer-launching refrigerator; Jack Black shares an antedote about meeting Jack Nicholson; CBS chief foriegn correspondent Lara Logan discusses reporting from war zones in Iraq and Afghanistan.
